Biobran MGN-3: Immune Support


BioBran MGN-3 is one of the most effective food supplements available for helping the body maintain a strong and healthy immune system.


Developed in Japan by Daiwa Pharmaceutical in 1992, BioBran is manufactured using a patented process to break down (pre-digest) rice bran using enzymes from Shitake mushrooms. The resulting compound contains a unique blend of hemicellulose nutrients such as arabinoxylan, as well as other short chain polysaccharides. This unique molecular fingerprint makes it significantly more effective than any other immune system supplement on the market today, giving the body its best opportunity to optimize its own natural healing mechanisms. According to M. Ghoneum, a professor of immunology at Drew University in the United States and a researcher with over 30 years experience, BioBran® MGN-3 is the most promising immune complex he has examined.

A lower dose version of Biobran called Biobran Plus which has 50mg of Biobran with added Vitamin D3 and inactive yeast has been developed for basic immune system maintenance.

How does BioBran MGN-3 help us maintain a strong immune system? Our immune system is comprised of an army of white blood cells — NK cells, T and B cells — which travel around inside us destroying the millions of intruding microbes that penetrate our bodies every day, as well as the thousands of newly infected or abnormal body cells that develop. BioBran MGN-3 gives our white blood cells the nutritional support to carry out their vital role energetically and efficiently, helping to optimize immune function.

Another advantage of BioBran MGN-3 is that it retains its effectiveness in the body even after a prolonged period of use – in other words, there is none of the usual drop-off effect over time that is common with many other nutritional supplements. BioBran is also highly absorbable, completely non-toxic, GMO-free and contains no actual mushroom in the finished product, which means it can be safely taken by those with mushroom intolerances. (The only situation when one should avoid using this product is obviously in conjunction with immunosuppressants.)

More information on this product can be found in good research libraries or on the internet (see our Links page). There is also a non-technical published book telling the story of BioBran, a book you can find in the Other Productssection in the top-left products menu.

For normal health maintenance, the recommended intake is 500mg per day with meals. Those who need optimum immune system support, take 3 grams per day for 8 weeks (1g with each meal), and then 1 gram per day thereafter.

BioBran MGN-3 is available in 50 x 250mg tablet blister pack (see pic), 30 & 105 x 1000mg (1g) powder sachets (see right) and a low-dose 90 x 50mg tablet version. Gram for gram, there is no difference in effectiveness between the powder, tablets and capsules. Generally those taking smaller quantities prefer the convenience of tablets whilst those taking larger quantities prefer sachets. The powder is very palatable and can be dissolved in a small amount of water. Tablets should be taken with meals, whereas sachets should ideally be taken 20 minutes after a meal.

Biobran tablet ingredients: Biobran Arabinoxylan compound (250mg per tablet), Microcystalline Cellulose (bulking agent ), Cornstarch (stabiliser), Cocoa Powder (colour), Glycerol Ester of Fatty Acids (emulsifier), Dextrin (stabilizer), Tricalcium Phosphate (anti-caking agent), Silicon Dioxide (anti-caking agent)

Biobran sachet ingredients (max dose): Biobran Arabinoxylan compound (1000mg per sachet), Microcrystaline Cellulose (bulking agent), Dextrin (stabiliser), Corn Starch (stabiliser), Tricalcium Phosphate (anti-caking agent).

Biobran Plus Tabs ingredients (for maintenance): Inactivated brewer’s yeast, BioBran Arabinoxylan compound (50mg per tablet), dextrin, microcrystalline cellulose, shellac coating, cocoa powder, sucrose fatty acids ester, Vitamin D3 (4.9 IU per tablet).

Additional information


50 tabs x 250mg, 30 sachets x 1000mg, 105 sachets x 1000mg, Biobran Plus 90tabs x 50mg, intro book – 100 pages

Tech Specs


Used nutritionally for:
Helps to regulate weak, compromised or unbalanced immune systems. Also helps reduce inflammation.

Available Sizes: 
50mg x 90 tablets (with added Vit D3 & inactive yeast)
250mg x 50 tablets
1000mg x 30 sachets
1000mg x 105 sachets

For normal health maintenance, the recommended intake is 500mg per day with meals. Those who need optimum immune system support, take 3 grams per day for 8 weeks (1g with each meal), and then 1 gram per day thereafter.

Not to be taken with immuno-suppressants

Side effects:
None known

Allergen information:
None known (contains small amounts of corn starch as a filler and the tablets contain insignificant amounts of cocoa as a natural colourant)

Dietary information:
Suitable for vegetarians and vegans except for the Biobran Plus which contains shelac and so is not suitable for vegans.

Suggested Combinations:
Combine with ProstaSol, Imupros and Curcumin Complex for prostate support. Combine with Imusan and Indole-3-Carbinol for breast support. Also is sometimes used in combination with TMAZ zeolite.

For more technical info:
Visit the Links section of this website.