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2024 August

Cordyceps: Nature's Powerhouse for Vitality and Well-being

16th August 2024

Luisa Carugati, BA, DipCNM

Cordyceps sinensis is a powertful therapeutic fungi species that provides a host of therapeutic benefits.

Cordyceps sinensis is a fascinating parasitic fungi that grows, in the wild, on the larvae of ghost months (Thitarodes) in the high Himalayan plateaus of Tibet, Nepal, Bhutan, and parts of India and China. For food supplements, however, this fungi is grown on nutrient-dense substrates of rice, barley, soybeans and other organic materials. In Traditional Chinese medicine, cordyceps are used in tonic form to boost the vitality and stamina of those feeling weak or fatigued.

The health benefits of Cordyceps are well-documented and stem from various powerful compounds found in the mushroom. These include:

  • Cordycepin: Known for its energy-boosting properties.
  • Cordymin: Helps with overall health and well-being.
  • Polysaccharides: Important for immune support.
  • Glycoproteins: Aid in cellular functions and communication.
  • Ergosterol: A precursor to vitamin D, which is crucial for bone health.

Together, these contribute to this fungi's reputation for:

Immune System Support

Cordyceps has shown promising effects on immune function, particularly in enhancing the activity of natural killer cells. These cells play a crucial role in the body's defence against infections and cancer. Research published in the Journal of Medicinal Food found that Cordyceps significantly increased the activity of natural killer cells, suggesting potential benefits for immune health. [1, 2]

Potential Anti-Aging Properties of Cordyceps

For centuries, Cordyceps mushrooms have been used by the elderly to combat fatigue, enhance strength, and boost vitality. Modern research suggests that the antioxidant properties of Cordyceps may be the key to their potential anti-aging effects.

Antioxidants are crucial molecules that help protect cells from damage caused by free radicals. Studies have demonstrated that Cordyceps can increase antioxidant levels in aged mice, resulting in improved memory and overall function. [3, 4, 5]

Research has provided some evidence of the potential longevity benefits of Cordyceps. For example, one study observed that mice given Cordyceps lived several months longer than those given a placebo. Cordyceps also showed potential for extending the lifespan of fruit flies in another research paper. [6]

Blood Sugar Regulation

Cordyceps mushrooms might be a natural way to help maintain healthy blood sugar levels. They contain a unique sugar that can act similarly to insulin, the hormone that helps move sugar from your blood into your cells for energy.

Research shows that Cordyceps can help keep blood sugar levels in check. Studies on mice found that these mushrooms helped lower blood sugar levels. There is also some evidence suggesting that Cordyceps might support kidney function. In a review of 22 studies with 1,746 people, those who took Cordyceps showed improved kidney function. [7, 8]

Potential Heart Health Benefits

Cordyceps may also support heart health. In China, these mushrooms are approved for supporting regular heartbeat. [9]

A study on rats showed that Cordyceps significantly reduced heart injuries. Researchers believe this benefit comes from adenosine, a compound in Cordyceps known for its heart-protective effects. [10]

Additionally, animal studies have found that Cordyceps can help maintain healthy cholesterol and triglyceride levels. [11, 12, 13]

Supporting a Healthy Inflammatory Response

Cordyceps might also help support a balanced inflammatory response in the body. While some inflammation is necessary for healing, maintaining a healthy inflammatory balance is crucial for overall well-being. [14, 15]

Studies have shown that Cordyceps can help regulate proteins involved in inflammation. This suggests that Cordyceps could be a useful supplement for supporting a healthy inflammatory response. For example, Cordyceps reduced inflammation in the airways of mice, indicating potential benefits for respiratory health.

Cordyceps may also help with skin health. In one study, applying Cordyceps topically helped reduce skin inflammation in mice.

Promoting Hormone Balance

Cordyceps may support steroidogenesis, the process by which steroids are produced in the body. Steroids like testosterone and estrogen are crucial for various bodily functions, from muscle health to reproductive well-being. Recent research suggests that compounds found in Cordyceps can enhance the production of these vital hormones by supporting adrenal gland function and improving overall endocrine balance. [16]

Athletic Performance Enhancement

Athletes have increasingly turned to Cordyceps for its potential to improve exercise performance. A study published in the Journal of Alternative and Complementary Medicine demonstrated that Cordyceps supplementation improved exercise performance in healthy older adults. This suggests that Cordyceps could be beneficial for both athletes and older individuals looking to maintain their physical capabilities. [17]

Liver Health Support

Research indicates that Cordyceps may have hepatoprotective effects, potentially benefiting liver health. A study published in the Journal of Ethnopharmacology found that Cordyceps extract showed protective effects against liver fibrosis. While more human studies are needed, this suggests potential applications for supporting liver function. [18]

Potential Anti-Tumor Properties

While research is still in early stages, some studies suggest that Cordyceps may have anti-tumor properties. A review published in the Journal of Pharmacy and Pharmacology discussed the potential anti-cancer effects of Cordyceps. However, it's important to note that more research, particularly human clinical trials, is needed to confirm these effects. [19]

Safety and Side Effects

While Cordyceps is generally considered safe for most people, it's important to be aware of potential side effects and interactions. Some individuals may experience mild side effects such as nausea or dry mouth. Cordyceps may also interact with certain medications, including blood thinners and immunosuppressants. As with any supplement, it's crucial to consult with a healthcare provider before adding Cordyceps to your regimen, especially if you have existing health conditions or are taking medications.

Traditional Uses in Chinese and Tibetan Medicine

In traditional Chinese and Tibetan medicine, Cordyceps has been used for centuries to treat a wide range of ailments. It was traditionally used to strengthen the lungs and kidneys, enhance sexual function, and boost overall vitality. In Tibet, it was often used as a tonic for the elderly to increase energy and reduce fatigue. Understanding these traditional uses can provide valuable context for modern applications of Cordyceps in holistic health practices.

About Myconutri Products

At The Really Healthy Company, we are proud to offer Myconutri medicinal mushrooms. Myconutri ensures the highest quality of all their mushroom products through careful selection of premium raw materials. Each supplier undergoes individual inspection, and all raw materials are rigorously tested by independent UK laboratories to meet the highest standards.

What sets Myconutri apart is their commitment to purity and potency. Their Cordyceps products are made from carefully cultivated mushrooms, ensuring a consistent and high-quality supplement. With Myconutri, you can trust that you're getting a premium product backed by scientific research and stringent quality control.

Ready to experience the potential benefits of Cordyceps for yourself? Explore our range of premium Myconutri Cordyceps products on our website [insert link here]. Your journey to better health and vitality starts with The Really Healthy Company.

Conclusion

Cordyceps mushrooms offer exciting potential benefits for supporting overall vitality, healthy aging, blood sugar regulation, heart health, balanced inflammatory responses, and hormone production. While many studies are promising, more research is needed to fully understand how these benefits apply to humans. As always, consult with a healthcare provider before adding any new supplement to your routine.

Remember, while Cordyceps is generally considered safe for most people, it's important to use it responsibly and under professional guidance, especially if you have any existing health conditions or are taking medications.

Please note, if you are unwell, we advise you to get a tailored treatment program from your healthcare practitioner.

References:

  1. Kim HG, Shrestha B, Lim SY, et al. Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur J Pharmacol. 2006;545(2-3):192-199.
  2. Zhou X, Luo L, Dressel W, et al. Cordycepin is an immunoregulatory active ingredient of Cordyceps sinensis. Am J Chin Med. 2008;36(5):967-980.
  3. Li SP, Zhang GH, Zeng Q, et al. Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia. Phytomedicine. 2006;13(6):428-433.
  4. Ji DB, Ye J, Li CL, Wang YH, Zhao J, Cai SQ. Antiaging effect of Cordyceps sinensis extract. Phytother Res. 2009;23(1):116-122.
  5. Wang J, Liu YM, Cao W, Yao KW, Liu ZQ, Guo JY. Anti-inflammation and antioxidant effect of Cordyceps militaris in high-fat diet-induced obese mice. Food Funct. 2015;6(9):3224-3232.
  6. Panda AK, Swain KC. Traditional uses and medicinal potential of Cordyceps sinensis of Sikkim. J Ayurveda Integr Med. 2011;2(1):9-13.
  7. Zhang HW, Lin ZX, Tung YS, et al. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease. Cochrane Database Syst Rev. 2014;(12):CD008353.
  8. Zhao CS, Yin WT, Wang JY, et al. Cordyceps mycelia extract ameliorates type 2 diabetes by modulating gut microbiota and improving glucose metabolism. Food Res Int. 2021;140:109950.
  9. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med. 1998;4(3):289-303.
  10. Patel S, Goyal A. Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech. 2012;2(1):1-15.
  11. Guo P, Kai Q, Gao J, et al. Cordycepin prevents hyperlipidemia in hamsters fed a high-fat diet via activation of AMP-activated protein kinase. J Pharmacol Sci. 2010;113(4):395-403.
  12. Yan W, Li T, Lao J, Song B, Shen Y. Anti-fatigue property of Cordyceps guangdongensis and the underlying mechanisms. Pharm Biol. 2013;51(5):614-620.
  13. Koh JH, Kim JM, Chang UJ, Suh HJ. Hypocholesterolemic effect of hot-water extract from mycelia of Cordyceps sinensis. Biol Pharm Bull. 2003;26(1):84-87.
  14. Kuo YC, Tsai WJ, Wang JY, Chang SC, Lin CY, Shiao MS. Regulation of bronchoalveolar lavage fluids cell function by the immunomodulatory agents from Cordyceps sinensis. Life Sci. 2001;68(9):1067-1082.
  15. Zhang Y, Li S, Wang X, et al. Cardioprotective effects of Cordyceps militaris polysaccharides: improving cardiac function, and modulating heart failure. Biomed Res Int. 2019;2019:5649612.
  16. Chen S, Li Z, Krochmal R, et al. Cordyceps militaris enhances steroidogenesis in mouse Leydig cells. J Ethnopharmacol. 2015;172:140-147.
  17. Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010;16(5):585-590.
  18. Peng J, Li X, Feng Q, et al. Anti-fibrotic effect of Cordyceps sinensis polysaccharide: Inhibiting HSC activation, TGF-β1/Smad signalling, MMPs and TIMP-1. Int J Biol Macromol. 2013;54:9-17.
  19. Yue K, Ye M, Zhou Z, Sun W, Lin X. The genus Cordyceps: a chemical and pharmacological review. J Pharm Pharmacol. 2013;65(4):474-493.

 

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